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Student Number 86341002
Author Fu-Hu Su(蘇富湖)
Author's Email Address No Public.
Statistics This thesis had been viewed 2123 times. Download 1688 times.
Department Chemical and Materials Engineering
Year 2000
Semester 2
Degree Ph.D.
Type of Document Doctoral Dissertation
Language zh-TW.Big5 Chinese
Title On NMR Signal and Rheology Properties of Crosslinked PDMS colloidal solution and its application to NMR Contrast Agent
Date of Defense 2001-06-15
Page Count 159
Keyword
  • colloidal solution
  • NMR contrast agent
  • PDMS
  • Abstract The objective of this study is to research the application of crosslinked PDMS (polydimethylsiloxane) to contrast agent of NMRI (nuclear magnetic resonance imaging) for gastro-intestine. With emulsification and hydrosilylation, the crosslinked PDMS can be homogeneously dispersed in water to form colloidal solutions. The characters of these colloidal solutions are ascertained by FTIR spectra, MTT assay, NMR images, laser light scattering, steady-shear rheology, dynamic-shear rheology, NMR spectra, T1 relaxation and T2 relaxation. MTT assay indicates these colloidal solutions have low toxicity and NMR images illustrate they can intensify contrast in in-vitro gastrointestinal images. Regarding the NMR properties of the crosslinked PDMS colloidal solutions and the linear PDMS emulsions, the conventional equations for T1 relaxation and T2 relaxation (eqn.(2-4) and eqn.(2-5)) do not agree with some of experimental results such as T1 relaxation of -(CH2CH2O)- segments and T2 relaxation of crosslinked PDMS, water as well as -(CH2CH2O)- segments. For the rheology behaviors, there is a peculiar difference between the volume fraction (ψ) greater than and smaller than a critical value (ψc). These specific NMR properties and rheology behaviors are discussed in detail in chapters 4 and 5 respectively. However, ψ
    Table of Content 封面
    封面
    目次
    目次
    第一章 緒綸
    第二章 文獻回顧
    1. 前言
    2. NMRI及其顯影劑
    3. 聚二甲基矽氧高分子(PDMS)之NMR性質
    4. 流變性質
    第三章 顯影劑之製備與特性分析
    1. 前言
    2. 實驗
    3. 結果與討論
    4. 結論
    第四章 顯影劑之NMR性質研究
    1. 前言
    2. 理論
    3. 結果與討論
    4. 結論
    第五章 顯影劑之流變性質研究
    1. 前言
    2. 理論
    3. 結果與討論
    4. 結論
    第六章 總結
    參考文獻
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