||1.Simpson, H. and Mckinlay, I., “Poisoning with slow-release fenfluramine,” Brit. Med. J., 4, 462-463, 1975. |
2.Bechgaard, H. and Cadefoged, K., “Gastrointestinal transit time of single-unit tablets,” J. Pharm. Pharmacol., 33, 791-792, 1981.
3.Gupta, P.K., Johnson, H. and Allexon, C., “In vitro and in vivo evaluation of polylactic acid microspheres for intramuscular drug delivery,” J. Control. Rel., 26, 229-238, 1993.
4.Beck, P., Kreuter, J. and Fichtner, I., “Influence of PBCA nanoparticles and liposomes on the toxicity of the anticancer drug mifoxantrone,” J. Microencapsul., 10, 101-114, 1993.
5.Hannia, T., Kreuter, J., Speiser, P., Boye, T., Gumy, R. and Kubis, A., “Enhancement of the myotic responce of rabbits with pilocarpine-loaded polybutylcyanoacrylate nanoparticles,” Int. J. Pharm., 33, 187-193, 1986.
6.Kanta, B., Couvreur, P., Lenaerts, V., Guiot, P., Roland, M., Baudhuim, P. and Speiser, P., “Tissue distribution of antitumor drugs associated with polyalkylcyanoacrylate nanoparticles,” J. Pharm. Sci., 69, 199-202, 1980.
7.Kante, B., Couverur, P., Meester, C.D., Guiot, P., Roland, M., Mercier, M. and Speiser, P., “Toxicity of polyalkylcyanoacrylate nanoparticles Ⅰ. Free nanoparticles,” J. Pharm. Sci., 71, 786-790, 1982.
8.Hirano, S. and Noishiki, Y., “The blood compatibility of chitosan and N-acetylchitosans,” J. Biomed. Mater. Res., 19, 413-417, 1985.
9.Shigehiro, H., Yashiro, K. and Junko, K., “Effect of sulfated derivatives of chitosan on some blood coagulant factors,” Carbohydr. Res., 137, 205-215, 1985.
10.Muzzarelli, R.A., “Biochemical significance of exogenous chitins and chitosan, in animals and patients,” Carbohydr. Polym., 20, 7-16, 1993.
11.David, P., Manssur, Y. and Mark, S., “Unusual susceptibility of chitosan to enzymic hydrolysis,” Carbohydr. Res., 237, 325-332, 1992.
12.Sashiwa, H., Saimoto, H., Shigemasa, Y., Ogawa, R. and Tokura, S., “Lysozyme susceptibility of partially deacetylated chitin,” Int. J. Biol. Macromol., 12, 295-296, 1990.
13.Aiba, S., “Studies on chitosan: 4. Lysozymic hydrolysis of partially N-acetylated chitosans,” Int. J. Biol. Marcromol., 14, 225-228, 1992.
14.Hirano, S. and Matsumura, T., “N-acyl derivatives of chitosan and their hydrolysis by chitonase,” Carbohydr. Res., 165, 120-122, 1987.
15.Brandenberg, G., Leibrock, L.G., Shuman, R., Malette, W.G. and Quigley, H., “Chitosan: a new topical hemostatic agent for diffuse capillary bleeding in brain tissue,” Neurosurgery., 15, 9-13, 1984.
16.Muzzarelli, R.A., Tanfani, F. and Emanuelli, M., “Sulfated N-carboxymethyl chitosan : Novel blood anticoagulants,” Carbohydr. Res., 126, 225-231, 1984.
17.Stanley, W.L., Watters, G.G., Kelly, S.H. and Olson, A.C., “Glucoamylase immobilized on chitin with glutaraldehyde,” Biotechnol. Bioeng., 20, 135-140, 1978.
18.Onsoyen, E. and Skaugrud, O., “Metal recovery using chitosan,” J. Chem. Tech. Biotechnol., 49, 395-404, 1990.
19.Muzzarelli, R.A.A., “Chitin and its derivatives: New trends of applied and research,” Carbohydr. Polym., 3, 52-57, 1993.
20.Ralston, G.B., Tracey, M.V. and Wrench, P.V., “The inhibition of fermentation in baker's yeast by chitin,” Biochim. Biophys. Acta., 93, 652-655, 1964.
21.Nishimura, S., Ikeuchi, Y. and Tokura, S., “The adsorption of bovine blood proteins onto the surface of O-carboxymethyl chitin,” Carbohydr. Res., 134, 305-312, 1984.
22.Inoue, K., Baba, Y. and Yoshizuka, K., “Selectivity series in the adsorption of mental ions on a resin prepared by crosslinking copper(Ⅱ)-complexed chitosan,” Chem. Lett., 1281-1284, 1988.
23.Chandy, T. and Sharma, C.P., “Prostaglandin El-immobilized poly(vmyl alcohol)-blended chitosan membranes: blood compatibility and permeability properties,” J. Appli. Polym. Sci., 44, 2145-2156, 1992.
24.Kifime, K., Yamaguchi, Y. and Kishimoto, S., “Wound healing effect of chitin surgical dressing,” Trans. Soc. Biomat., XI, 216-220, 1988.
25.Pelletir, A., Lemire, L. and Sygnsch, J., “Chitin卅chitosan transformation by thermo- chemical treatment,” Biotechnol. Bioeng., 36, 310-315, 1990.
26.Peluso, G., Petille, O., Ranieri, M., Santin, M.,Ambrosio, L., Calabro, D., Avallone, B. and Balsamo, G., “Chitosan-mediated stimulation of macrophage function,” Biomaterials, 15, 1215-1220, 1994.
27.Sakaguchi, T., Horikoshi, T. and Nakajima, A., “Adsorption of uraniumby chitin phosphate and chitosan phosphate,” Agric. Biol. Chem., 45, 2191-2195, 1981.
28.Hassan, E.E., Parish, R.C. and Gallo, J.M., “Optimized formulation of magnetic chitosan microspheres containing the anticancer agent, oxantrazole,” Pharm. Res., 9, 390-397, 1992.
29.Ohya, Y., Shiratami, M. and Ouchi, T., “Release behavior of 5-FU from chitosan gel nanospheres immobilizing 5-FU coated with polysaccharides,” J. Macro. Sci., 31, 629-642, 1994.
30.Ohya, Y., Takei, T. and Ouchi, T., “Thermo-sensitive release behavior of 5-FU from chitosan-gel microspheres coated with lipid layer,” J. Bioact. & Compat. Polym., 7, 242-256, 1992.
31.Nishioka, Y., Kyotani, S., Okamura, M., Miyazaki, M., Okazaki, K., Ohnishi, S., Yamamoto, Y., and Ito, K., “Release characteristics of cisplatin chitosan microspheres and effect of containing chitin,” Chem. Pharm. Bull., 38, 2871-2873, 1990.
32.Akbuga, J. and Bergisadi, N., “5-Fluorouracil-loaded chitosan microspheres: preparation and release characteristics,” J. Microencapsul., 13, 161-168, 1996.
33.Jameela, S.R., Misra, A. and Jayakrishnan, A., “Cross-linked chitosan microspheres as carriers for prolonged delivery of macromolecular drugs,” J. Biomat. Sci. Polym. Edn., 6, 621-632, 1994.
34.Jameela, S.R., Kumary, T.V., Lal, A.V. and Jayakrishnan, A., “Progesterone-loaded chitosan microspheres: a long acting biodegradable controlled delivery system,” J. Control. Rel., 52, 17-24, 1998.
35.Jameela, S.R. and Jayakrishnan, A., “Glutaraldehyde cross-linked chitosan microspheres as a long acting biodegradable drug delivery vehicle: studies on the in vitro release of mitoxantrone and in vivo degradation of microspheres in rat muscle,” Biomaterials, 16, 769-775, 1995.
36.Alexakis, T., Boadi, D.K., Quong, D., Groboillot, A., O'Neill, I., Poncelet, D. and Neufeld, R.J., “Microencapsulation of DNA within alginate microspheres and crosslinked chitosan membranes for in vivo application,” Appli. Biochem. Biotechnol., 50, 93-106, 1995.
37.Thanoo, B.C., Sunny, M.C. and Jayakrishnan, A., “Cross-linked chitosan microspheres: preparation and evaluation as a matrix for the controlled release of pharmaceuticals,” J. Pharm. Pharmacol., 44, 283-286, 1992.
38.Thacharodi, D. and Panduranga R.O., “Development and in vitro evaluation of chitosan-based transdermal drug delivery systems for the controlled delivery of propanolol hydrochloride,” Biomaterials, 16, 145-148, 1995.
39.Sezer, A.D. and Akbuga, J., “Release characteristics of chitosan treated alginate beads: I. Sustained release of a macromolecular drug from chitosan treated alginate beads,” J. Microencapsul., 16, 195-203, 1999.
40.Thacharodi, D. and Rao K.P., “Propranolol hydrochloride release behaviour of crosslinked chitosan membranes,” J. Chem. Technol. Biotechnol., 58, 177-181, 1993.
41.Groboillot, A.F., Champagne, C.P., Darling, G.D., Poncelet, D. and Neufeld, R.J., “Membrane formation by interfacial cross-linking of chitosan for microencapsulation of lactococcus lactis,” Biotechnol. Bioeng., 42, 1157-1163, 1993.
42.Freeman, A. and Dror, Y., “Immobilization of disguised yeast in chemically crosslinked chitosan beads,” Biotechnol. Bioeng., 44, 1083-1088, 1994.
43.Shinonaga, M.A., Kawamura, Y. and Yamane, T., “Immobilization of yeast cells with cross-linked chitosan beads,” J. Ferment. and Bioeng., 74, 90-94, 1992.
44.Chanda, J., Kuribayashi, R. and Abe, T., “Use of the glutaraldehyde-chitosan treated porcine pericardium as a pericardial substitute,” Biomaterials, 17, 1087-1091, 1996.
45.Thacharodi, D. and Rao, K.P., “Rate-controlling biopolymer membranes as transdermal delivery systems for nifedipine: development and in vitro evaluations,” Biomaterials, 17, 1307-1311, 1996.
46.Yao, K.D., Peng, T., Yin, Y.J. and Xu, M.X., “ Microcapsules/Microspheres related to chitosan,” J. Macromol. Sci. Rev. Marcomol. Chem. Phys., 35, 155-180, 1995.
47.Kim, J.H., Kim, J.Y., Lee, Y.M. and Kim, K.Y., “Controlled release of riboflavin and insuline through crosslinked poly(vinyl alcohol)/chitosan blend membrane,” J. Appli. Polym. Sci., 44, 1823-1828, 1992.
48.Turkov, J., Brod, C. and Stamberg, J., “Proteolytic, dry biopolymeric composition for treatment of wounds, and method of using same,” U.S. Patent, No. 4613502, 1-6, 1986.
49.Maletle, W.G., Omaha, P.L. and Quigley, H.J., “Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound,” U.S. Patent No. 4532134, 1-8, 1985.
50.Jackson, D.S. and Princeton, N.J., “Chitosan-glycerol-water gel,” U.S. Patent, No. 4659700, 1-4, 1987.
51.Desoize, B., Jardillier, J.C., Kanoun, K., Guerin, D. and Levy, M.C., “In-vitro cytotoxic activity of cross-linked protein microcapsules,” J. Phann. Pharmacol., 38, 8-13, 1986.
52.Mauger, A.D., Benoit, J.P. and Puisieux, F., "Preparation and characterization of cross-linked human serum albumin microspheres containing 5-fluorouracil,” Pharm. Acta. Helv., 61, 119-124, 1986.
53.Nishi, C., Nakajima, N., Ikada, Y., “In vitro evaluation of cytotoxicity of diepoxy compounds used for biomaterial modification,” J. Biomed. Mater. Res., 29, 829-834, 1995.
54.Gendler, E., Gendler, S. and Nimni, M.E., “Toxic reactions evoked by glutaraldehyde-fixed pericardium and cardiac valve tissue bioprosthesis,” J. Biomed. Mater. Res., 18, 727-736, 1984.
55.Speer, D.P., Chvapil, M., Eskelson, C.D. and Ulreich, J., “Biological effects of residual glutaraldehyde in glutaraldehyde-tanned collagen biomaterials,” J. Biomed. Mater. Res., 14, 753-764, 1980.
56.Huang-Lee, L.L.H., Cheung, D.T. and Nimni, M.E., “Biochemical changes and cytotoxicity associated with the degradation of polymeric glutaraldehyde derived crosslinks,” J. Biomed. Mater. Res., 24, 1185-1201, 1990.
58.Fujikawa, S., Yokota, T., Koga, K. and Kumada, S.I., “The continuous hydrolysis of geniposide to genpin using immobilized β-glucosidase on calcium alginate gel,” Biotechnol. Lett., 9, 697-702, 1987.
59.Kimura, Y., Okuda, H. and Archi, S., “Effects of geniposide isolated from Gardenia jasminoides on metabolic alterations in high sugar diet-fed rats,” Chem. Pharm. Bull., 30, 4444-4447, 1982.
60.Wang, C.J., Wang, S.W. and Lin, J.K., “Suppressive effect of geniposide on the hepatotoxicity and hepatic DNA binding of aflatoxin B1 in rats,” Caner. Lett., 60, 95-102, 1991.
61.Tseng, T.H., Chu, C.Y. and Wang, C.J., “Inhibition of penta-acetyl geniposide on AFB1-induced genotoxicity in C3H10T1/2 cells,” Cancer. Lett., 62, 233-242, 1992.
62.Miwa, T., Jap. J. Pharmacol., 2, 102-108, 1953.
63.Miwa, T., Jap. J. Pharmacol., 2, 139-143, 1953.
64.Miwa, T., Jap. J. Pharmacol., 3, 1-5, 1953.
65.Sung, H.W., Huang, R.N., Huang, L.L.H. and Tsai, C.C., “In vitro evalualtion of cytotoxicity of a naturally occurring crosslinking reagent for biological tissue fixation,” J. Biomat. Sci. Polym. Edn., 13, 63-78, 1999.
66.Sung, H.W., Huang, R.N., Huang, L.L.H., Tsai, C.C. and Chiu, C.T., “Feasibility study of a natural crosslinking reagent for biological tissue fixation,” J. Biomed. Mater. Res., 42, 560-567, 1998.
67.Huang, L.L.H, Sung, H.W., Tsai, C.C. and Huang, D.M., “Biocompatibility study of a biological tissue fixed with a naturally occuring crosslinking reagent,” J. Biomed. Mater. Res., 42, 568-576, 1998.
68.Silvestro, L., Viano, I., Macario, M., Colangelo, D., Montrucchio, G., Panico, S. and Fantozzi, R., "Effects of heparin and its desulfated derivatives on leukocyte-endothelial adhesion," Semin. Thromb. Hemost., 20, 254-258, 1994.
69.Sung, H.W., Huang, D.M., Chang, W.H., Huang, R.N. and Hsu, J.C., "Evaluation of Gelatin Hydrogel Crosslinked with Various Crosslinking Agents as Bioadhesives: In Vitro Study," J. Biomed. Mater. Res., 46, 520-530, 1999.
70.Nimini, M.E., Cheung, D., Strate, B., Kodama, M. and Sheikh, K., “Bioprosthesis derived from cross-linked and chemically modified collagenous tissues,” in collagen Vol. III, M.E., Nimini (ed.), CRC Press, Boca Raton, Florida, 1-38, 1988.
72.Tanigawa, T., Tanaka, Y., Sashiwa, H., Saimoto, H. and Shigemasa, Y., “Various biological effects of chitin derivatives,” In Advances in chitin and chitosan, Elsevier Applied Science, London and New York, 206-215, 1992.
73.Young, D.H., Kohle, H. and Kauss, H., “Effect of chitosan on membrane permeability of suspension-cultured Glycine max and Paseolus vulgaris cells,” Plant Physiol., 70, 1449-1454, 1982.
74.Leuba, J.L. and Stossel, P., “Chitosan and other polyamines: antifungal activity and interaction with biological membranes,” Chitin in Nature and Technology, 215-221, 1986.
75.Tsai, G.J. and Su, W.H., “Antibacterial activity of shrimp chitosan against Escherichia coli,” J. Food Prot., 62, 239-243, 1999.
76.Mori, T., Okumura, M., Matsuura, M., Ueno, K., Tokura, S., Okamoto, Y., Minami, S. and Fujinaga, T., “Effects of chitin and its derivatives on the proliferation and cytokine production of fibroblasts in vitro,” Biomaterials, 18, 947-951, 1997.
77.Ellerhorst, J., Nguyen, T., Cooper, D.N., Estrov, Y., Lotan, D. and Lotan, R., “Induction of differentiation and apoptosis in the prostate cancer cell line LNCaP by sodium butyrate and galectin-1,” Int. J. Onco., 14, 225-32, 1999.